The direct great circle path to Cape Horn drops down to 65S so ice gates have been placed at 48S to keep the high tech speedsters safely north. At the start there's a high to the east (see figure below) which will drive the boats south from the start, seeking the stronger westerlies at 50S.
A key question is how much pure southerly and how much a bit of easterly, but that will probably depend each boat's sweet spots and best points of sail. After that..... lets see what the weather brings.Graphic from www.metvuw.com